Author

Alaa’ Lufti Melhem

University of DundeeORCID 0000-0002-7316-2700Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:eQTL / molecular QTL mapping· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Adem Y. DawediD· 2 shared Alasdair TayloriD· 2 shared Colin N A PalmeriD· 2 shared Ewan R. PearsoniD· 2 shared Margherita BigossiiD· 2 shared Moneeza Kalhan SiddiquiiD· 2 shared Sundararajan SrinivasaniD· 2 shared Alison D. McNeillyiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Adem Y. DawedORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintMay 4, 2023

XBP1 expression in pancreatic islet cells is associated with poor glycaemic control across ancestries especially in young non-obese onset diabetes

Théo Dupuis, Ranjit Mohan Anjana, Sundararajan Srinivasan…·Moneeza Kalhan Siddiqui

This study identifies XBP1 expression in pancreatic islets as a genetic factor associated with poor glycaemic control and increased T2DM risk in South and East Asians, particularly in young non-obese onset diabetes.

DOI 10.1101/2023.05.04.23289501

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintAug 9, 2022

Common and rare variants in SLCO1B1 are associated with statin intolerance

Margherita Bigossi, Cyrielle Maroteau, Adem Y. Dawed…·Moneeza Kalhan Siddiqui

This study shows that considering both loss-of-function and gain-of-function variants in SLCO1B1 improves the prediction of statin intolerance compared to using only the Val174Ala variant.

DOI 10.1101/2022.08.09.22278584

humanGWAS summary statistics

𝕏 PostBluesky