Author

Nicole B. Rockweiler

Washington University in St. LouisORCID 0000-0001-5249-5357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Avinash RamuiD· 2 shared Casey W. DrubiniD· 2 shared Donald F. ConradiD· 2 shared Abir MohsiniD· 1 shared Alec Wysoker· 1 shared Andrew W. KraftiD· 1 shared Antonino ZitoiD· 1 shared Barak A. CoheniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Avinash RamuORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 23, 2026

Common variation of cell abundances and gene expression in the human striatum

Steven Burger, Olivia Yoo, James C. Nemesh…·Steven A. McCarroll

The paper analyzes single-nucleus RNA-seq data from the human striatum and prefrontal cortex to study inter-individual variation in cell abundances and gene expression, finding age-related changes and genetic associations.

DOI 10.64898/2026.03.20.713160

humanscRNA-seq

𝕏 PostBluesky

GenomicsSciencePeer-reviewedApr 13, 2023

The origins and functional effects of postzygotic mutations throughout the human lifespan

Nicole B. Rockweiler, Avinash Ramu, Liina Nagirnaja…·Donald F. Conrad

This study maps postzygotic mutations across tissues and lifespan, showing their functional variation and selection pressures, suggesting multiple dynamic genomes per individual.

36 citationstop 3%

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 21, 2018

Somatically Mutated Genes Under Positive and Negative Selection Found by Transcriptome Sequence Analysis Include Oncogene and Tumor Suppressor Candidates

Casey W. Drubin, Avinash Ramu, Nicole B. Rockweiler, Donald F. Conrad

The paper identifies somatically mutated genes under positive and negative selection and links them to oncogenic processes using transcriptome sequence analysis.

DOI 10.1101/396739

humanbulk RNA-seq

𝕏 PostBluesky