BioinformaticsbioRxivPreprint
DNA-binding domain-aware classification enables systematic annotation of the regulatory genome
Christian Ickes, Cigdem Hazal Timucin, Bendix Christian Harms…·Martin Haubrock
TFClassPredict is a DNABERT-based framework that classifies DNA-binding domains to annotate regulatory elements, outperforming existing methods and enabling lineage-specific TF program reconstruction.