Carol Brayne

The DPUK Data Portal provides secure access to cohort data for dementia research, supporting multi-modal analyses and collaborations across multiple institutions.

The paper uses a novel gene-based analysis approach to identify three novel genes associated with Alzheimer’s disease using genome-wide association data.

This study investigates how dopamine levels in Parkinson’s disease patients affect sensory attenuation during voluntary movements, finding a negative correlation with motor severity and a positive correlation with dopamine dose.

This study examines the associations between cardiovascular risk factors and white matter structure in aging, finding that systolic blood pressure, diastolic blood pressure, and heart rate independently impact white matter health.

The paper shows that physical activity preserves frontal white matter integrity and reduces age-related slowing in a population-based sample.