Cell BiologyBlood AdvancesPeer-reviewed
The zebrafish model tackles anti-P2Y12 variability in humans: a translational approach
Paulina Ciepla, Richard J. Fish, Séverine Nolli…·Pierre Fontana
This paper uses zebrafish models to study miR-150's role in platelet function and resistance to P2Y12 inhibitors, finding that miR-150 downregulates MASTL, leading to reduced VASP phosphorylation and clopidogrel resistance in humans.
DOI 10.1182/bloodadvances.2025019008