Ted Schwaba

This study identifies 1,257 genetic variants associated with human personality traits using large-scale GWAS and finds widespread genetic correlations with behaviors and life outcomes.

This study evaluates transdiagnostic polygenic risk scores for psychiatric disorders using the All of Us Research Program data, finding that a common psychiatric genetic factor PRS better predicts comorbidity burden than single-disorder scores.

The paper compares the multivariate genetic architecture of eight psychiatric disorders between males and females using Genomic Structural Invariance, finding similarities and sex-specific differences in genetic factor loadings.

The paper introduces GTACCC to assess genetic continuity and differentiation of negative emotionality and MDD across severity, finding increasing genetic sharing with severity.

The paper tests if socioeconomic gradients observed in blood DNA methylation measures can be reproduced using buccal-cell DNA, finding smaller effect sizes and lower cross-tissue correlations.