Molecular BiologybioRxivPreprint
SETD2 Deficiency Promotes Inflammatory Bowel Disease via Oxidative Stress and FasL-induced Apoptosis
Yueduo Wang, Shenghai Shen, Li Li
This study shows that SETD2 deficiency in mice leads to increased oxidative stress and FasL-induced apoptosis in intestinal epithelial cells, contributing to IBD pathogenesis.
DOI 10.1101/2022.11.10.516012