Author

Shenghai Shen

Hong Kong University of Science and TechnologyORCID 0000-0001-8422-5423Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Beifang LuiD· 1 shared Jiadai HuangiD· 1 shared Letong XuiD· 1 shared Li LiiD· 1 shared Lisheng ZhangiD· 1 shared Runsheng LiiD· 1 shared Xin DengiD· 1 shared Yitong Shen· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Beifang LuORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivMay 13, 2025

Quantitative RNA pseudouridine landscape reveals dynamic modification patterns and evolutionary conservation across bacterial species

Letong Xu, Shenghai Shen, Yizhou Zhang…·Xin Deng

This study maps pseudouridine modifications across bacterial species, revealing dynamic patterns and evolutionary conservation, and develops a deep learning framework for predicting modified sites.

3 citations

E. colibacteria (other)

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Molecular BiologybioRxivPreprintNov 10, 2022

SETD2 Deficiency Promotes Inflammatory Bowel Disease via Oxidative Stress and FasL-induced Apoptosis

Yueduo Wang, Shenghai Shen, Li Li

This study shows that SETD2 deficiency in mice leads to increased oxidative stress and FasL-induced apoptosis in intestinal epithelial cells, contributing to IBD pathogenesis.

DOI 10.1101/2022.11.10.516012

mousebulk RNA-seq

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