Tinca J. C. Polderman

This study reviews sex differences in additive genetic effects related to autism, finding inconclusive evidence but suggesting higher polygenic scores in females without intellectual disability.

This paper reviews and meta-analyzes studies using the autism polygenic score to assess its association with autism diagnosis and related traits, finding moderate associations with diagnosis and weaker links with traits.

This study identifies genetic variants associated with antisocial behavior through a genome-wide association meta-analysis, finding significant links to FOXP2 and correlations with multiple health and behavioral traits.

This study analyzes 4,155 GWASs to explore pleiotropy and genetic architecture across 558 traits, finding that most loci are associated with multiple traits and causal variants are enriched in coding and regulatory regions.

This study identifies 202 genome-wide significant loci for insomnia using a large sample, linking them to specific brain cell types and pathways.

The paper analyzes rare coding variants in smoking and drinking behavior using exome chip data, finding that they contribute to phenotypic variation but require larger samples for individual variant associations.

The paper estimates genetic correlations between antisocial behavior and life history traits using GWAS data, finding positive and negative associations with reproductive output and delayed reproductive onset, respectively.

This study conducts a large GWAS meta-analysis of neuroticism, identifying 136 novel genetic loci and 599 genes, with functional insights into brain regions and pathways.