Author

Yann Abraham

ORCID 0000-0001-5600-5896Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Alessandro RomualdiiD· 1 shared Andrew Paul CopeiD· 1 shared Annabelle SmalliD· 1 shared Carl Coyle· 1 shared Deepak A. RaoiD· 1 shared Elie Hatem· 1 shared Gabrielle Antonio-CarreoniD· 1 shared Garrett S. DunlapiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperSystems Biology

Alessandro RomualdiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 30, 2026

Persistent circulating autoreactive PD1⁺TIGIT⁺ peripheral helper T cells reflect synovial lymphoid activity and poor response to conventional disease-modifying anti-rheumatic drugs in early rheumatoid arthritis

Jia Yi Hee, Hendrik J. Nel, Oxana Radetskaya…·Ranjeny Thomas

DOI 10.64898/2026.07.28.740434

humanflow cytometry

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Systems BiologybioRxivPreprintMar 6, 2026

TwinCell: Large Causal Cell Model for Reliable and Interpretable Therapeutic Target Prioritisation

Jean-Baptiste Morlot, Thomaz Lüscher Dias, Sébastien Légaré…·Yann Abraham

TwinCell identifies therapeutic targets by analyzing cell state transitions using a causal model trained on in vitro data, outperforming existing methods in both virtual and clinical settings.

3 citations

humanbulk RNA-seq

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