Author

Shakson Isaac

Broad InstituteORCID 0000-0001-5631-3469Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scATAC-seq· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Accelerating Medicines Partnership® RA/SLE Program and Network· 1 shared Adam T. Chicoine· 1 shared Alessandra NervianiiD· 1 shared Alkes L. PriceiD· 1 shared Ami Ben‐Artzi· 1 shared Amit LakhanpaliD· 1 shared Andrew C. CordleiD· 1 shared Andrew D. FileriD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Accelerating Medicines Partnership® RA/SLE Program and Network

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1 paper

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedApr 1, 2024

Tissue-specific enhancer-gene maps from multimodal single-cell data identify causal disease alleles

Saori Sakaue, Kathryn Weinand, Shakson Isaac…·Soumya Raychaudhuri

The paper develops SCENT, a method to create cell-type-specific enhancer-gene maps from single-cell multimodal data, identifying causal variants and genes for diseases.

64 citationstop 1%

humanscRNA-seq

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