SPP1hi macrophages in fibrin niches promote hyperplastic tissue remodeling in rheumatoid arthritis synovium
Ian Mantel, Haoxuan Zhang, Juan Vargas…·Thomas Eisenhaure
SPP1hi macrophages in RA synovial fibrin deposits promote tissue hyperplasia.
Author
Brigham and Women's Hospital
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Ian Mantel, Haoxuan Zhang, Juan Vargas…·Thomas Eisenhaure
SPP1hi macrophages in RA synovial fibrin deposits promote tissue hyperplasia.
C. A. Donado, Erin Theisen, Fan Zhang…·Michael B. Brenner
This study identifies granzyme K as a driver of a novel complement activation pathway independent of classical, lectin, or alternative pathways.
Saori Sakaue, Kathryn Weinand, Shakson Isaac…·Soumya Raychaudhuri
The paper develops SCENT, a method to create cell-type-specific enhancer-gene maps from single-cell multimodal data, identifying causal variants and genes for diseases.
Joyce B. Kang, Amber Z. Shen, Saisriram Gurajala…·Joseph E. Powell
The paper maps cell-type-specific eQTLs for HLA genes across multiple tissues and identifies dynamic regulation of HLA-DQ genes in immune cells.
Fan Zhang, Anna Helena Jonsson, Aparna Nathan…·Zhu Zhu
The paper deconstructs RA synovium using single-cell data to identify six cell type abundance phenotypes associated with distinct inflammatory states.