Author

Preston B. Moore

Saint Joseph's UniversityORCID 0000-0001-5633-9087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1 Organism:virus· 1

Frequent Co-Authors

Artiom Butuc· 1 shared Eleonora GiantiiD· 1 shared Hannah Gibbs· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Artiom Butuc

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintMay 29, 2026

Preorganized RdRp-Thumb Dynamics Drives SARS-CoV-2 Polymerase Function

Hannah Gibbs, Artiom Butuc, Preston B. Moore, Eleonora Gianti

This study uses MD simulations to show that preorganized thumb-subdomain motions in SARS-CoV-2 polymerase drive functional transitions through structurally coupled regulatory regions.

DOI 10.64898/2026.05.29.728794

virusstructural biology

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