NeurosciencebioRxivPreprint
Chronic social defeat stress induces meningeal neutrophilia via type I interferon signaling
Stacey L. Kigar, Mary-Ellen Lynall, Allison E. DePuyt…·Miles A. Herkenham
Chronic social defeat stress increases meningeal neutrophils via type I interferon signaling from skull bone marrow, contributing to behavioral issues, and blocking this pathway reduces neutrophil trafficking and improves behavior.