Investigation of immune response to Mesenchymal Stromal Cell-derived Extracellular Vesicles in the cancer setting
Katie Gilligan, Oliver Treacy, Clodagh P. O’Neill, Elan C. McCarthy, Emma A. McDermott, Elma Mammen, Peter Dockery, Aideen E. Ryan, Róisín M. Dwyer
This study investigates whether MSC-EVs elicit an immune response in tumor-bearing mice and finds no significant immune activation, supporting their immune privilege and therapeutic potential.
bioRxiv · Jan 28, 2025 · PreprintCancer Biology