Ruoyu Zhang

scEPS integrates GWAS and single-cell data to identify disease-associated cell neighborhoods by testing gene expression variance explained in disease contexts.

This study evaluates normalization/imputation methods in scRNA-seq, finding that preprocessing introduces spurious correlations and proposes a noise regularization method to remove these artifacts.

STAMP is a sequencing method for efficiently measuring mtDNA heteroplasmies and content, showing high accuracy and cost-effectiveness for population studies.