Author

Wei Keat Lim

Regeneron (United States)ORCID 0000-0002-6226-2570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Arny A. FerrandoiD· 1 shared Asiel Arturo BeniteziD· 1 shared Benjamin DanieliD· 1 shared Brian Klotz· 1 shared Carley TaskeriD· 1 shared Christina AdleriD· 1 shared Francesco Pinto BoenoiD· 1 shared Gurinder S. AtwaliD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPhysiology

Arny A. FerrandoORCID

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3 papers

Recent·Most cited

PhysiologybioRxivPreprintSep 24, 2026

Spatial Transcriptomics Identifies Muscle Inflammation Susceptibility as a Distinct Periarticular Skeletal Muscle Phenotype in End-Stage Knee Osteoarthritis

Francesco Pinto Boeno, Zachary Graham, Qi Su…·Marcas M. Bamman

DOI 10.64898/2026.09.16.752138

humanspatial transcriptomics

𝕏 PostBluesky

ImmunologybioRxivPreprintJul 27, 2026

Multiomics profiling of APECED peripheral blood highlights compositional increases in alternatively activated B cell subsets

William Galbavy, Hyunjin Kim, Brian Klotz…·Sokol A. Haxhinasto

This study identifies compositional changes in B cell subsets in APECED patients, highlighting expanded alternatively activated B cells with autoreactive potential.

DOI 10.64898/2026.07.24.740518

𝕏 PostBluesky

BioinformaticsPatternsPeer-reviewedFeb 16, 2021

Noise regularization removes correlation artifacts in single-cell RNA-seq data preprocessing

Ruoyu Zhang, Gurinder S. Atwal, Wei Keat Lim

This study evaluates normalization/imputation methods in scRNA-seq, finding that preprocessing introduces spurious correlations and proposes a noise regularization method to remove these artifacts.

22 citations

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