Systems BiologybioRxivPreprint
Kinome profiling allows examination and prediction of kinase inhibitor cardiotoxicity
Jimmy S. Tabet, Chinmaya U. Joisa, Brian C. Jensen, Shawn M. Gomez
The paper uses proteomic kinome profiling and machine learning to predict kinase inhibitor cardiotoxicity by analyzing off-target kinase engagement and its association with cardiac adverse events.
DOI 10.64898/2026.04.03.716310