Author

Haruaki Nobori

Shionogi (Japan)ORCID 0000-0001-5735-0843Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Akihiro Hori· 1 shared Hirofumi SawaiD· 1 shared Hiromitsu Shibayama· 1 shared Jun SatoiD· 1 shared Kana Kurahashi· 1 shared Keiichiro Hirai· 1 shared Kenji NakaharaiD· 1 shared Masayuki TakamatsuiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Akihiro Hori

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1 paper

Recent·Most cited

BiochemistryJournal of Medicinal ChemistryPeer-reviewedJul 5, 2025

Discovery of The Clinical Candidate S-892216: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19

Yuto Unoh, Keiichiro Hirai, Shota Uehara…·Yuki Tachibana

This paper describes the discovery of S-892216, a potent SARS-CoV-2 3CLpro inhibitor with antiviral activity against multiple variants and low cross-resistance to existing drugs.

27 citationstop 1%

experimental assaydrug response / drug discovery

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