Joseph R. Ecker

This paper introduces snmCT-seq, a multi-omic method that profiles transcriptome and DNA methylome from single nuclei, enabling accurate cell type classification in human tissues.

This paper introduces snmC-seq2, an improved single-cell DNA methylome profiling method that enhances read mapping, reduces artifacts, and increases throughput and coverage uniformity.

This paper presents a high-quality, contiguous genome assembly of Arabidopsis thaliana using a single Nanopore flow cell and consumer hardware, demonstrating cost-effectiveness and scalability.

This paper introduces FALCON and FALCON-Unzip algorithms to assemble diploid genomes from SMRT sequencing data, demonstrating improved contiguity and phasing compared to short-read methods.