Accurate chromosome-scale haplotype-resolved assembly of human genomes
Shilpa Garg, Arkarachai Fungtammasan, Andrew W. Carroll, Mike Chou, Anthony Schmitt, Xiang Zhou, Stephen Mac, Paul Peluso, Emily Hatas, Jay Ghurye, Jared Maguire, Medhat Mahmoud, Haoyu Cheng, David Heller, Justin M. Zook, , Heng Li
This paper introduces a method for chromosome-scale haplotype-resolved genome assembly using long reads and long-range data, achieving high accuracy and contiguity in three human genomes.
bioRxiv · Jul 1, 2020 · PreprintBioinformatics