Cancer BiologyNature CommunicationsPeer-reviewed
Targeting PRMT3 Impairs Methylation and Oligomerization of HSP60 to Boost Anti-Tumor Immunity by Activating cGAS/STING Signaling
Yunxing Shi, Zongfeng Wu, Shaoru Liu…·Binkui Li
This study identifies PRMT3 as a driver of immunotherapy resistance in HCC, showing that targeting it enhances anti-tumor immunity via cGAS/STING activation.
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