Author

Safirul Islam

Presidency UniversityORCID 0000-0001-5859-1331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 4

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chandrama MukherjeeiD· 4 shared Avik MukherjeeiD· 1 shared Dániel KissiD· 1 shared Pinaki Ghosh· 1 shared Rachel E. KieseriD· 1 shared Utpal BakshiiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 8 mutual co-author links

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4 shared papersMolecular Biology

Chandrama MukherjeeORCID

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4 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 1, 2026

Cytoplasmic capping enzyme targeted, hypoxia-responsive RNAs, RORA and KCTD16 modulate the aggressiveness of CoCl2-induced hypoxic osteosarcoma cells

Safirul Islam, Utpal Bakshi, Chandrama Mukherjee

The paper identifies RORA and KCTD16 as hypoxia-responsive RNAs stabilized by cCE that suppress osteosarcoma cell aggressiveness by inhibiting c-Myc.

DOI 10.64898/2026.03.30.715387

humanbulk RNA-seq

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Molecular BiologyBiochimica et Biophysica Acta (BBA) - Gene Regulatory MechanismsPeer-reviewedApr 6, 2025

Hypoxia inducible factor HIF1α elevates expression of mRNA capping enzyme during cobalt chloride-induced hypoxia

Safirul Islam, Chandrama Mukherjee

This study shows that CoCl2-induced hypoxia increases capping enzyme (CE) expression via HIF1, which stabilizes target lncRNAs under hypoxic conditions.

2 citations

statistical model

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Molecular BiologybioRxivPreprintNov 21, 2024

Identification of transcriptome-wide cobalt chloride-induced hypoxia-responsive long noncoding RNAs regulated by cytoplasmic mRNA capping enzyme

Pinaki Ghosh, Safirul Islam, Chandrama Mukherjee

The paper identifies hypoxia-responsive lncRNAs regulated by cytoplasmic mRNA capping enzyme in osteosarcoma cells under cobalt chloride-induced hypoxia.

DOI 10.1101/2024.11.21.624636

humanbulk RNA-seq

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Molecular BiologyFEBS LettersPeer-reviewedMar 1, 2023

Identification of long non-coding RNAs as substrates for cytoplasmic capping enzyme

Avik Mukherjee, Safirul Islam, Rachel E. Kieser…·Chandrama Mukherjee

The paper investigates whether long non-coding RNAs are substrates for cytoplasmic capping enzyme by analyzing their subcellular localization and uncapped forms.

11 citations

humanbulk RNA-seq

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