Author

Hans G. Lilja

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-5871-7846Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:GWAS / association mapping· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:GWAS summary statistics· 2 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Robert J. KleiniD· 4 shared Christopher A. HaimaniD· 3 shared David V. ContiiD· 3 shared John P. ShelleyiD· 3 shared John S. WitteiD· 3 shared Jonathan D. MosleyiD· 3 shared Kerry Roe SchafferiD· 3 shared Linda KachuriiD· 3 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Robert J. KleinORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Genetic & Genomic MedicineHuman Genetics and Genomics AdvancesPeer-reviewedJun 6, 2024

Transcriptome-Wide Association Analysis Identifies Novel Candidate Susceptibility Genes for Prostate-Specific Antigen Levels in Men Without Prostate Cancer

Dorothy M. Chen, Ruocheng Dong, Linda Kachuri…·Rebecca E. Graff

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

Genetic & Genomic MedicinemedRxivPreprintOct 27, 2023

Genome-wide association study of prostate-specific antigen levels in 392,522 men identifies new loci and improves cross-ancestry prediction

Thomas J. Hoffmann, Rebecca E. Graff, Ravi Madduri…·John S. Witte

This study identifies 447 new genetic variants associated with prostate-specific antigen levels across multiple ancestries and shows improved cross-ancestry prediction of PSA, with implications for personalized prostate cancer screening.

3 citations

humanGWAS summary statistics

𝕏 PostBluesky

Genetic & Genomic MedicineNature MedicinePeer-reviewedJun 1, 2023

Genetically Adjusted PSA Levels for Prostate Cancer Screening

Linda Kachuri, Thomas J. Hoffmann, Yu Jiang…·John S. Witte

This study develops a polygenic score to adjust PSA levels, improving the detection of aggressive prostate cancer while reducing unnecessary biopsies.

80 citationstop 4%

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsGenePeer-reviewedOct 26, 2020

Validation of Prostate Cancer Risk Variants by CRISPR/Cas9 Mediated Genome Editing

Xing Wang, James E. Hayes, Xing Xu…·Robert J. Klein

The paper validates prostate cancer risk SNPs using CRISPR/Cas9 to show they alter MSMB expression, highlighting the importance of functional studies in GWAS findings.

18 citations

humanGWAS summary statistics

𝕏 PostBluesky