Author

Upneet K. Sokhi

Hospital for Special SurgeryORCID 0000-0001-5907-5646Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anne R. BassiD· 1 shared Anvita SingarajuiD· 1 shared Bikash MishraiD· 1 shared Karmela K ChaniD· 1 shared Laura T. DonliniD· 1 shared Lionel B. IvashkiviD· 1 shared Richard D. BelliD· 1 shared Ruoxi YuaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Anne R. BassORCID

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1 paper

Recent·Most cited

ImmunologyeLifePeer-reviewedJul 15, 2025

Opposing Regulation of TNF Responses by IFN-γ and a PGE2-cAMP Axis that is Apparent in Rheumatoid and Immune Checkpoint Inhibitor-induced Arthritis IL-1β+ Macrophages

Upneet K. Sokhi, Ruoxi Yuan, Bikash Mishra…·Lionel B. Ivashkiv

This study identifies a PGE2-cAMP axis that opposes IFN-γ regulation of TNF responses in IL-1β+ macrophages in RA and ICI-arthritis, revealing a novel regulatory mechanism for inflammatory gene expression.

9 citations

humanscRNA-seq

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