Author

Anvita Singaraju

Hospital for Special SurgeryORCID 0000-0002-3109-6354Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:eQTL / molecular QTL mapping· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Laura T. DonliniD· 3 shared Lionel B. IvashkiviD· 3 shared Aaron J. WyseiD· 2 shared Adam T. Chicoine· 2 shared Alessandra NervianiiD· 2 shared Ami Ben‐Artzi· 2 shared Amit LakhanpaliD· 2 shared Andrew C. CordleiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Laura T. DonlinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologyeLifePeer-reviewedJul 15, 2025

Opposing Regulation of TNF Responses by IFN-γ and a PGE2-cAMP Axis that is Apparent in Rheumatoid and Immune Checkpoint Inhibitor-induced Arthritis IL-1β+ Macrophages

Upneet K. Sokhi, Ruoxi Yuan, Bikash Mishra…·Lionel B. Ivashkiv

This study identifies a PGE2-cAMP axis that opposes IFN-γ regulation of TNF responses in IL-1β+ macrophages in RA and ICI-arthritis, revealing a novel regulatory mechanism for inflammatory gene expression.

9 citations

humanscRNA-seq

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ImmunologyNaturePeer-reviewedFeb 6, 2025

Granzyme K drives a newly-intentified pathway of complement activation

C. A. Donado, Erin Theisen, Fan Zhang…·Michael B. Brenner

This study identifies granzyme K as a driver of a novel complement activation pathway independent of classical, lectin, or alternative pathways.

154 citationstop 1%

humanproteomics

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Genetic & Genomic MedicineNature GeneticsPeer-reviewedNov 30, 2023

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

Joyce B. Kang, Amber Z. Shen, Saisriram Gurajala…·Joseph E. Powell

The paper maps cell-type-specific eQTLs for HLA genes across multiple tissues and identifies dynamic regulation of HLA-DQ genes in immune cells.

49 citationstop 1%

humanbulk RNA-seq

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