Author

Ru‐Yi Zhu

National University of SingaporeORCID 0000-0001-5908-2555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Junsong Guo· 2 shared Song Chen· 2 shared Tuan‐Khoa KhaiD· 2 shared Yiran ZhaoiD· 2 shared Baixi CHEN· 1 shared Chunyi HuiD· 1 shared Senfeng ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

Junsong Guo

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2 papers

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedAug 18, 2026

Small Molecule-Directed RNA Modification via Proximity-Driven Catalysis

Song Chen, Tuan‐Khoa Kha, Yiran Zhao…·Ru‐Yi Zhu

This paper introduces a small molecule-directed method for site-selective RNA modification using DMAP catalysis and proximity-driven acylation, validated across multiple RNA types.

DOI 10.1021/jacs.6c13298

bulk RNA-seqexperimental assay

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BiochemistryAngewandte Chemie International EditionPeer-reviewedAug 5, 2026

Nitro Reduction-Based RNA Control and Ultrafast Release

Yiran Zhao, Senfeng Zhang, Junsong Guo…·Ru‐Yi Zhu

This paper introduces a reversible RNA modification strategy using nitro reduction to control RNA function and release, applicable across various RNA types and contexts.

DOI 10.1002/anie.9746658

experimental assay

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