Palayakotai R. Raghavan

This study shows metadichol induces CD14 expression in hESCs but downregulates it in fibroblasts, demonstrating cell-type-specific modulation of CD14.

This study shows metadichol induces an inverted U-shaped expression pattern of TLRs and related genes in PBMCs, suggesting a dose-dependent effect on immune regulation.

This study shows metadichol modulates TLR expression in cancer cell lines, upregulating some TLRs and downregulating others, with potential therapeutic applications in cancer and inflammation.

This study shows metadichol increases expression of CRY1, CLOCK, and PPARGC1A in human fibroblasts, but not PER1 or BMAL1, suggesting indirect effects on circadian clock genes.