Author

Katherine Welker Leng

University of MichiganORCID 0000-0001-6021-5159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

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Carol A. FierkeiD· 1 shared Julia K. VargaiD· 1 shared Kelsey DiffleyiD· 1 shared Ora Schueler‐FurmaniD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperMolecular Biology

Carol A. FierkeORCID

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1 paper

Recent·Most cited

Molecular BiologyScientific ReportsPeer-reviewedFeb 2, 2022

Structure-based prediction of KDAC6 substrates validated by enzymatic assay reveals determinants of promiscuity and detects new potential substrates

Julia K. Varga, Kelsey Diffley, Katherine Welker Leng…·Ora Schueler‐Furman

The paper predicts HDAC6 substrates using a structure-based method calibrated by enzymatic assays, identifies new substrates, and highlights structural determinants of HDAC6 promiscuity.

15 citations

proteomicsstatistical model

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