Leqi Tian

NicheScope identifies multicellular niches and their regulated cell states from spatial transcriptomics data, revealing tissue structures and clinically relevant tumor niches.

fast-scBatch corrects batch effects in scRNA-seq data using a neural network-driven approach, outperforming existing methods in simulation and real datasets.

The paper introduces a statistical method to identify spatially associated biological pathways, finding significant pathways linked to spatial variation in human and mouse datasets.