IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data
Tiam Heydari, Matthew A. Langley, Cynthia L. Fisher, Daniel Aguilar‐Hidalgo, Shreya Shukla, Ayako Yachie‐Kinoshita, Michael R. Hughes, Kelly Marshall McNagny, Peter W. Zandstra
IQCELL predicts gene perturbation effects on developmental trajectories using scRNA-seq data, showing it can infer over 75% of known causal gene interactions in mouse T-cell development.
PLoS Computational Biology · Feb 25, 2022Peer-reviewedSystems Biology