Author
California Institute of TechnologyORCID 0000-0003-2890-5584Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Christina J. Su, Arvind Murugan, James M. Linton…·Michael B. Elowitz
The paper develops a mathematical model to show how promiscuous ligand-receptor interactions enable efficient cellular addressing through combinatorial signaling.
Heidi E. Klumpe, Matthew A. Langley, James M. Linton…·Michael B. Elowitz
The paper investigates how BMP ligands interact combinatorially and context-dependently through receptor expression, revealing equivalence groups and a biochemical model for signaling complex formation.
Tiam Heydari, Matthew A. Langley, Cynthia L. Fisher…·Peter W. Zandstra
IQCELL predicts gene perturbation effects on developmental trajectories using scRNA-seq data, showing it can infer over 75% of known causal gene interactions in mouse T-cell development.
Ayako Yachie‐Kinoshita, Kento Onishi, Joel Östblom…·Peter W. Zandstra
The paper develops a computational model using Boolean logic to predict pluripotent stem cell fate transitions in response to signaling inputs.