Author

E Chan

National University of SingaporeORCID 0000-0001-6107-9072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

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Anastasiia TikhonovaiD· 1 shared Hao FaniD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBioinformatics

Anastasiia TikhonovaORCID

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1 paper

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BioinformaticsJournal of Chemical Information and ModelingPeer-reviewedJan 13, 2026

Enhancing CYP450-Ligand Binding Predictions: A Comparative Analysis of Ligand-Based and Hybrid Machine Learning Models

Anastasiia Tikhonova, E Chan, Hao Fan

This paper compares ligand-based and hybrid machine learning models for predicting CYP450 ligand binding, finding the hybrid model outperforms existing methods in accuracy.

DOI 10.1021/acs.jcim.5c01098

machine learning (classical)drug response / drug discovery

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