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Nicheformer: a foundation model for single-cell and spatial omics
Anna Christina Schaar, Alejandro Tejada-Lapuerta, Giovanni Palla…·Fabian Joachim Theis
Pretrained on 57 million dissociated and 53 million spatial human and mouse cells, a 49.3M-parameter transformer predicts niche, region, neighborhood composition and density, and carries spatial labels onto scRNA-seq.