Jianzhi Zhang

The paper introduces COL, a computational pipeline that identifies putatively functional back-splicing events by integrating three features, achieving lower false positive rates than existing methods.

The paper shows that genetic maintenance of same-sex sexual behavior has declined due to contraception reducing the reproductive impact of having more sexual partners.

The paper provides proteomic evidence supporting the translational accuracy hypothesis of codon usage bias across over 1000 taxa, showing codon-specific translational accuracies correlate with tRNA abundance.

This study uses allele-specific single-cell RNA sequencing to estimate intrinsic and extrinsic gene expression noise in mouse fibroblasts and identifies factors influencing these noises.

The paper shows that gene expression co-fluctuates across distant genes on the same chromosome due to chromatin dynamics and gene linkage.

The paper identifies 181 yeast genes absent from the reference genome and validates their role in environmental adaptations using reverse genetics and association mapping in Saccharomyces cerevisiae.