Author

Bryan A. Moyers

HudsonAlpha Institute for Biotechnology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Gregory M. CooperiD· 2 shared R MyersiD· 2 shared Beth MartiniD· 1 shared Brian P. H. MetzgeriD· 1 shared Brian S. RobertsiD· 1 shared Brittany N. LasseigneiD· 1 shared Calum J. Maclean· 1 shared David E. Gray· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersGenomics

Gregory M. CooperORCID

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3 papers

Recent·Most cited

Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

Brian S. Roberts, E. Christopher Partridge, Bryan A. Moyers, Vikram Agarwal, Kimberly M. Newberry, Beth Martin, Jay Shendure, R Myers, Gregory M. Cooper

The paper shows that MPRA data exhibit strand asymmetry favoring naturally transcribed strands, suggesting biological functions driving this effect across gene bodies and Alu elements.

Genome Research · May 1, 2021Peer-reviewedGenomics

Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory alleles

J. Nicholas Cochran, Emily McKinley, J. Nicholas Cochran, Michelle D. Amaral, Bryan A. Moyers, Brittany N. Lasseigne, David E. Gray, James M.J. Lawlor, Jeremy W. Prokop, Ethan G. Geier, James Holt, Michelle L. Thompson, J. Scott Newberry, Jennifer S. Yokoyama, Elizabeth A. Worthey, , Erik D. Roberson

Genome sequencing for early-onset dementia identified genetic variants in 50% of patients, including pathogenic variants and moderate penetrance alleles, supporting an oligogenic model.

Molecular Case Studies · Dec 13, 2019Peer-reviewedNeuroscience

Deciphering the genic basis of environmental adaptations by simultaneous forward and reverse genetics in Saccharomyces cerevisiae

Calum J. Maclean, Brian P. H. Metzger, Jian‐Rong Yang, Wei-Chin Ho, Bryan A. Moyers, Jianzhi Zhang

The paper identifies 181 yeast genes absent from the reference genome and validates their role in environmental adaptations using reverse genetics and association mapping in Saccharomyces cerevisiae.

Molecular Biology and Evolution · May 2, 2017Peer-reviewedGenomics