Author

Karthik Amudhala Hemanthakumar

University of HelsinkiORCID 0000-0001-6151-1005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

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Andrey AnisimoviD· 1 shared Eero M. A. Mervaala· 1 shared Mikko Ilari MäyränpääiD· 1 shared Riikka KiveläiD· 1 shared Shentong FangiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperMolecular Biology

Andrey AnisimovORCID

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1 paper

Recent·Most cited

Molecular BiologyeLifePeer-reviewedMar 4, 2021

Cardiovascular disease risk factors induce mesenchymal features and senescence in cardiac endothelial cells

Karthik Amudhala Hemanthakumar, Shentong Fang, Andrey Anisimov…·Riikka Kivelä

This study shows that cardiovascular disease risk factors alter the transcriptome of cardiac endothelial cells, promoting mesenchymal features and senescence, with SERPINH1/HSP47 as a potential therapeutic target.

36 citations

humanbulk RNA-seq

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