Charles H. Langley

The paper introduces Centrolign, a tool for aligning centromeric regions, revealing mutation dynamics and enabling variant calling in human centromeres.

This paper identifies two ancient structural variants in walnut and hickory species that control heterodichogamy, a mating system with distinct genetic mechanisms in each genus.

The paper presents a comprehensive analysis of fully assembled human centromeres, revealing their architecture, variation, and evolutionary dynamics at high resolution.

The paper constructs high-quality genome annotations for six Juglans species and one outgroup, revealing gene family contractions and an ancient whole genome duplication in Juglandaceae.

The paper identifies large-scale haplotypes spanning centromeric regions in humans, revealing deep diversity including Neanderthal introgressions and ancient African lineages.

The paper reassembles and integrates 605 Drosophila melanogaster genomes using an improved alignment strategy, creating the Drosophila Genome Nexus for population genomic research.