Külli Kingo

This study shows miR-378a-3p enhances inflammatory responses in keratinocytes by modulating NF-κB pathways, potentially contributing to atopic dermatitis severity.

This study identifies genetic risk factors associated with severe psoriasis and shows that polygenic risk scores can predict severe disease outcomes better than traditional risk factors.

This study identifies 440 genes/proteins associated with atopic dermatitis severity through multi-omics analyses and highlights four with significant cross-evidence, including CEP85, which may contribute to severity via impaired phagocytosis.

This study performs a GWAS meta-analysis of psoriasis, identifying 109 susceptibility loci, including 45 new ones, and highlights potential therapeutic targets and disease mechanisms.

The paper integrates genetic and epigenetic data to identify autoimmune-specific enhancer dysregulation in CD4+ T cells and its role in disease pathogenesis.