Min Chen

This study shows ACAN promotes aortic dissection by disrupting mitochondrial homeostasis in VSMCs via the YAP1/TAZ pathway, and its reduction improves disease outcomes.

This study isolates climate-driven ecosystem productivity changes and shows they shift crop use to animal feed and bioenergy, and reorganize food systems across different socioeconomic scenarios.

This study constructs animal models to simulate different stages of DVT-APTE-CTEPD/CTEPH progression and compares their effectiveness in capturing pathological features.

CoMM-S2 uses GWAS summary statistics to infer mechanistic roles of genetic variants in gene expression, achieving performance comparable to methods using individual-level data.