Author

Saeko Tahara

University of TsukubaORCID 0000-0001-6343-2589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

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Haruka OzakiiD· 1 shared Hirotaka MatsumotoiD· 1 shared Takaho TsuchiyaiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBioinformatics

Haruka OzakiORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintApr 8, 2022

MOCCS profile analysis clarifies the cell type dependency of transcription factor-binding sequences and cis-regulatory SNPs in humans

Saeko Tahara, Takaho Tsuchiya, Hirotaka Matsumoto, Haruka Ozaki

The paper introduces MOCCS profiles to analyze DNA-binding specificity of TFs across cell types and shows that one-third of TFs exhibit cell-type-specific binding, with ΔMOCCS2scores predicting variant effects on TF binding.

DOI 10.1101/2022.04.08.487641

humanChIP-seq

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