Author

Elizabeth Elton

Ellison Medical InstituteORCID 0000-0001-6357-7809Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Nolan M. UngiD· 2 shared Shannon M. MumenthaleriD· 2 shared Abigail Coleman· 1 shared Benedikt Vilji Magnússon· 1 shared Brandon Choi· 1 shared Carly StreleziD· 1 shared Danielle HixoniD· 1 shared Eileen FungiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBioengineering

Nolan M. UngORCID

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Author profile →

3 papers

Recent·Most cited

Systematic modeling of phenotypic drug response profiles inpatient-derived organoids

Seungil Kim, Einar Bjarki Gunnarsson, Michael E. Doche, Yuyuan Zhou, Yukai Huang, Scott Valena, Pratiksha Kshetri, Elizabeth Elton, Nolan M. Ung, Abigail Coleman, Benedikt Vilji Magnússon, Niki Torab, Lara Papasian, Brandon Choi, Eileen Fung, , Shannon M. Mumenthaler

The paper introduces SCOPE, a method using AI and time-lapse imaging to classify drug responses in organoids into four phenotypic groups, identifying new drug effects and therapeutic uses.

bioRxiv · Jul 31, 2026 · PreprintBioengineering

Cancer-associated fibroblasts drive metabolic heterogeneity in KRAS-mutant colorectal cancer cells

Elizabeth Elton, Niki Tavakoli, Handan Çetin, Stacey D. Finley

This study uses computational methods to show that CAF-conditioned media increases metabolic heterogeneity in KRAS-mutant CRC cells following enzyme knockdowns.

bioRxiv · Sep 30, 2025 · PreprintSystems Biology

A novel thin plate spline methodology to model tissue surfaces and quantify tumor cell invasion in organ-on-chip-models

Elizabeth Elton, Carly Strelez, Nolan M. Ung, Rachel G. Perez, Kimya Ghaffarian, Danielle Hixon, Naim Matasci, Shannon M. Mumenthaler

The paper introduces a thin plate spline method to model tissue boundaries in organ-on-chip models and quantify tumor cell invasion.

SLAS DISCOVERY · May 23, 2024Peer-reviewedBioinformatics