Author

Frank Löhr

Goethe University FrankfurtORCID 0000-0001-6399-9497Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Volker DötschiD· 2 shared Alp Eren KazariD· 1 shared Andreas KrämeriD· 1 shared Arthur L. Haas· 1 shared Çağdaş DağiD· 1 shared Cansu Deniz Tozkoparan Ceylan· 1 shared Christopher LenziD· 1 shared Emine Sonay ElginiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Volker DötschORCID

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2 papers

Recent·Most cited

BiochemistryACS Chemical BiologyPeer-reviewedDec 8, 2025

Overcoming Ligand Discovery Challenges: Developing Peptide-Based Tracers for SPSB2

Christopher Lenz, Lewis Elson, Johannes Dopfer…·Stefan Knapp

This study develops peptide-based tracers for SPSB2 E3 ligase by conjugating cell-penetrating peptides to degrons, enabling efficient cellular delivery and target engagement assessment.

DOI 10.1021/acschembio.5c00702

proteomicsexperimental assay

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BiochemistrybioRxivPreprintJun 14, 2025

Dynamic hotspots in the Uba7 UFD direct UbcH8 recognition

Çağdaş Dağ, Mahil Lambert, Alp Eren Kazar…·Emine Sonay Elgin

This paper presents the NMR structure and functional analysis of the Uba7 UFD domain and its interaction with UbcH8, revealing structural flexibility and key residues critical for E2 recognition in the ISGylation pathway.

DOI 10.1101/2025.06.14.659664

humanexperimental assay

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