Author

Dongdong Yang

Cooperative Institute for Research in Environmental SciencesORCID 0000-0001-6473-8301Unclaimed ORCID profile · follow to get notified of new preprints

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Dongdong Yang1 paper · University of Science and Technology of China

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

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Karl A. WidneyiD· 1 shared Leo M. RuschiD· 1 shared Shelley D. CopleyiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperSynthetic Biology

Karl A. WidneyORCID

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintMar 19, 2024

CRISPR-Cas9-assisted genome editing in E. coli elevates the frequency of unintended mutations

Karl A. Widney, Dongdong Yang, Leo M. Rusch, Shelley D. Copley

The paper identifies unintended mutations in E. coli genomes after CRISPR-Cas9 editing, showing 26% of clones have mutations over 10 kb away from intended sites.

1 citation

E. coliwhole-genome sequencing

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