Author

Yasamin Fazeli

University of California, IrvineORCID 0000-0001-6477-3369Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Alyaa ShmaraiD· 2 shared Cheng ChengiD· 2 shared Lan Nguyen WeissiD· 2 shared Michele CarreriD· 2 shared Pallabi PaliD· 2 shared Paymaan Jafar‐NejadiD· 2 shared Tamar R. Grossman· 2 shared Victoria Boock· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alyaa ShmaraORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 25, 2025

Antisense oligonucleotides targeting Valosin-containing protein improve muscle pathology and molecular defects in cell and mouse models of multisystem proteinopathy.

Pallabi Pal, Michele Carrer, Lan Nguyen Weiss…·Virginia E. Kimonis

This study shows that antisense oligonucleotides targeting VCP reduce disease pathology and improve muscle function in cell and mouse models of multisystem proteinopathy.

DOI 10.1101/2025.07.25.665261

humanmouse

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Molecular BiologyClinical and Translational MedicinePeer-reviewedApr 1, 2025

Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease

Lan Nguyen Weiss, Michele Carrer, Alyaa Shmara…·Virginia E. Kimonis

This study shows that ASO-mediated Gys1 knockdown in a mouse model of Pompe disease reduces glycogen accumulation and improves motor function, both alone and in combination with ERT.

4 citations

mouseexperimental assay

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