SLD5/GINS4 controls dynein-dependent centrosome maturation and exposes a candidate mitotic vulnerability in cancer.
Vipin Kumar, Vivek Singh, R M Singh, Praveen Kumar, Tanushree Ghosh
This study shows SLD5/GINS4 regulates dynein-dependent centrosome maturation and identifies it as a potential therapeutic target in replication-driven cancers.
bioRxiv · May 11, 2026 · PreprintCancer Biology