Helle Smedegaard Hansson

The paper compares var gene expression in asymptomatic Plasmodium falciparum infections and clinical malaria cases during dry and wet seasons in Mali, finding fewer and lower-level var transcripts in asymptomatic carriers.

The paper introduces a new computational pipeline for var gene expression analysis, showing changes in var gene expression and core transcriptome during in vitro culture of Plasmodium falciparum.

The paper identifies PfEMP1 variants associated with severe malaria in first-time infected adults and non-severe cases using RNA-seq and var gene analysis.