Author

Thorsten Thye

Bernhard Nocht Institute for Tropical MedicineORCID 0000-0002-8941-006XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Anna BachmanniD· 1 shared Anna SchöllhorniD· 1 shared Benno KreuelsiD· 1 shared Birgit Muntau· 1 shared Christian G. MeyeriD· 1 shared Craig John KinneariD· 1 shared Egbert TannichiD· 1 shared Eileen Garner HoaliD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Anna BachmannORCID

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2 papers

Recent·Most cited

Gene expression profiling of malaria parasites reveals common virulence gene expression in adult first-time infected patients and severecases

Jan Stephan Wichers-Misterek, Gerry Q. Tonkin‐Hill, Thorsten Thye, Ralf Krumkamp, Benno Kreuels, Jan Strauss, Heidrun von Thien, Judith A. M. Scholz, Helle Smedegaard Hansson, Rasmus Weisel Jensen, Louise Turner, Freia-Raphaella Lorenz, Anna Schöllhorn, Iris Bruchhaus, Egbert Tannich, , Anna Bachmann

The paper identifies PfEMP1 variants associated with severe malaria in first-time infected adults and non-severe cases using RNA-seq and var gene analysis.

eLife · Apr 28, 2021Peer-reviewedMolecular Biology

A multi-phenotype genome-wide association study of clades causing tuberculosis in a Ghanaian- and South African cohort

Stéphanie Muller, Haiko Schurz, Gerard C. Tromp, Gian D van der Spuy, Eileen Garner Hoal, Paul D. van Helden, Ellis Owusu‐Dabo, Christian G. Meyer, Birgit Muntau, Thorsten Thye, Stefan Niemann, Robin M. Warren, Elizabeth Maria Streicher, Marlo Möller, Craig John Kinnear

This study performs a genome-wide association analysis of host genetic variants and MTBC strain infection in two cohorts, identifying 32 SNPs significantly associated with infection risk in the Ghanaian cohort.

Genomics · Apr 20, 2021Peer-reviewedGenetic & Genomic Medicine