Developmental BiologybioRxivPreprint
CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX
Aldo Ciau‐Uitz, Philip Pinheiro, Arif Kirmizitas…·Roger K. Patient
The paper shows that CBFβ can regulate gene expression independently of Runx, challenging the dogma that CBFβ's gene regulatory functions require Runx binding.