Lorenz Hexemer

The paper introduces SegmentNT, a DNA foundation model for genome annotation, achieving state-of-the-art performance in identifying 14 genic and regulatory elements across species.

The paper links TGFβ signaling, gene expression, and cellular fate decisions in mammary epithelial cells, identifying transcriptional regulators that ensure specific responses at high TGFβ doses.

ChatNT is a conversational agent that understands biological sequences and achieves state-of-the-art results on genomics tasks while being accessible to non-coders.